Undenatured Collagen Type II Retain The Complete Triple-Helix Molecular Structure of Collagen

• Customization: Available
• CAS No.: 9007-34-5
• Formula: C4h6n2o3r2
• Model NO.: Collagen
• EINECS: Undenatured Collagen Type II
• Type: UC II Powder
• Appearance: Powder
• Quality: Refined
• Colour: White
• Supply Type: Obm(Original Brand Manufacturing)
• Usage Mode: 100% Derived From Chicken Sternum Cartilage
• Suitable for: Tablets, Hard Capsules,Granules,Oral Drinks,Solid
• Form: Powder
• Application: Repair Degenerative Osteoarthritis and Promote Car
• MOQ: 1kg
• Shelf of Time: 2 Years
• Customized: OEM: Free Print Logo
• Express Company: FedEx,Sea Transportation
• Sample: 10g
• Brand: Bouliga
• Transport Package: 1kg with Double Plastic Container Inside/Aluminum
• Specification: 35ml*4ml*35ml
• Trademark: Bouliga
• Origin: China
• HS Code: 3006700000
• Production Capacity: 5kg/Month

Product Description

The molecule of collagen is composed of three polypeptide chains, each of which is a left - handed helix. The three chains are twisted together to form a right - handed super - helix, with approximately 30 amino acid residues per turn. UC - II keeps this native triple - helix structure intact, which is crucial for its biological function. This structure allows UC - II to bind tightly with polysaccharides, providing flexibility to cartilage, helping it absorb shocks and bear loads

UC II Functions

• Immune Regulation1: The main mechanism of UC - II is "oral immune tolerance". After being taken orally, UC - II, as an antigen, reacts with Peyer's patches in the intestine. The naive T - cells in the patches, upon contact with the UC - II antigen, transform into regulatory T - cells that recognize type II collagen as "self - antigen". These regulatory T - cells then travel to the articular cartilage and convey the information that type II collagen is "self - antigen" to the immune cells that are attacking the cartilage, causing these immune cells to stop secreting pro - inflammatory factors and start secreting anti - inflammatory factors, thereby blocking joint inflammation.
• Cartilage Repair and Regeneration1: In addition to blocking inflammation, regulatory T - cells also secrete cell growth factors, which activate the ability of chondrocytes to synthesize cartilage matrix, promoting the repair and regeneration of cartilage, and ultimately improving the health of cartilage.
• Anti - Inflammatory Effect2: UC - II may help reduce inflammatory responses, especially in joint inflammation, by regulating the immune system and reducing the secretion of inflammatory

  UC II Application

   

• Dietary Supplements5: Due to its convenience, safety, non - toxicity, and antigen - specificity, UC - II has become one of the commonly used dietary supplements for improving osteoarthropathy. It can help relieve joint swelling and pain, repair damaged joints, and inhibit inflammation.
• Biomedical Field7: In tissue engineering, UC - II can be used as a scaffold material to promote cell adhesion, proliferation, and differentiation, thereby repairing damaged tissues. In regenerative medicine, it can be used as part of the extracellular matrix to promote cell migration and differentiation, facilitating tissue regeneration. In drug delivery, UC - II can be used as a carrier to carry drug molecules and target them to specific sites, improving the efficacy of drugs and reducing side effects.

  UC II Characteristics

• Patented Technology: The production of UC - II usually adopts patented low - temperature extraction technology to ensure the integrity of the triple - helix structure.
• High Purity: It has a high content of undenatured type II collagen, with strict quality control standards for appearance, smell, form, and physical and chemical properties. For example, the color is usually cream - colored or light yellow, with a characteristic smell of collagen, and it is in the form of a fine powder.

 

Product Name	Undenatured Collagen Type II			Batch No.	20240505
Source	Chicken Sternum Cartilage	Specifications	Powder	Batch Weight	1250kg
Manuf. Date	May 05, 2024	Testing Date	May 06, 2024	Report Date	May 08, 2024
Expiry Date	May 04, 2026	Packing	25kg/drum	Standard	Inner quality standard
Items		Standard			Result
Appearance		Off white powder			Pass
Odor		, Slightly salty.with characteristic odor of this product			Pass
Impurity		No visible exogenous impurity			Pass
Stacking Density,g/ml		----			0.64
Mucopolysaccharide(%)		≥26.00			33.1
Undenatured Collagen Type II(%)HPLC		≥15.0			20.2
Protein(%, 5.79)		≥60.0			63.7
Ash(%)		≤8.0			6.0
Moisture(%)		≤10.0			7.8
pH(2%) aqueous solution		5 .0~7.0			6.4
Fat(%)		≤6.0			0.1
Lead(Pb)mg/kg		≤0.9			Pass
Chromium(Cr)mg/kg		≤2.0			Pass
Total plate count, CFU/g		n=5,c=2,m=10^4,M=10^5			Pass
Coliforms,CFU/g		n=5,c=2,m=10,M=100			Pass

 

 

 

Company Profile

Shandong Bouliga Biotechnology Co., Ltd. is located in a world-famous historical and cultural city,It is the hometown of Confucius, a world-renowned thinker and educator.
The company a professional supplier of high-quality sodium hyaluronate powder to the world. The company has been focusing on the research and development, production and sales of sodium hyaluronate for a long time, providing high-quality services throughout the process. our company's sodium hyaluronate mainly covers food grade, cosmetic grade, pharmaceutical grade and various high-end sodium hyaluronate, we can also provide professional customized services to meet customers' needs for products with different molecular weights and various packaging specifications.
Adhering to the principle of pursuing development with integrity, taking science and technology as the guide, pursuing reputation with quality, we have become an international manufacturer and supplier of sodium hyaluronate raw materials.
"It is a great pleasure to have friends coming from afar"! We look forward to working together with customers at home and abroad to create a win-win future!